开头首先要注意称呼的准确使用，确定信收信人的身份和称谓，如使用Dear Mr./Ms.表示正式的敬称，Dear + 名称则可表示亲近或熟悉程度不太高但仍有一定关系的朋友、亲戚等。
首先，表明写信的目的：I am writing to… 或 I am writing in order to…
接着，恭维对方，表示问候和感谢：I hope this letter finds you well. 或 Thank you very much for your help last time.
然后，谈论主要内容：The purpose of my letter is to… 或 I would like to inquire about…
在信中，要注意运用一些礼貌用语以及相应的语气：Would it be possible to… 或 Would you mind… 或 Could you please…
最后，表达自己的期待：I would be grateful if you could… 或 Thank you for considering my request. 或 I hope to hear from you soon.
再次感谢对方的帮助和支持，结束信件：Thank you again for your time and attention.
Yours sincerely 或 Yours faithfully,
Dear Mr. Chen,
I am writing to inquire about the possibility of attending your upcoming business conference on December 15th. I hope this letter finds you well and thank you for considering my request.
I have been following your company’s work and I find it both innovative and inspiring. I believe that attending the conference would be an invaluable opportunity to grow my professional network and learn from some of the industry’s leaders.
Would it be possible to provide me with more information about the conference and the registration process? I would be grateful if you could also let me know if there are any available scholarships for young professionals.
Thank you again for your time and attention. I hope to hear from you soon.